Contribution of the Nucleus Cuneiformis to the Antinociceptive Effects of Systemic Morphine on Inflammatory Pain in Rats
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چکیده
behaviors have already been demonstrated. Systemic morphine inhibited both the early and late phases of the formalin-induced licking responses, and this action was naloxone-sensitive (Dubuisson & Dennis, 1977; Oluyomi, Hart, & Smith, 1992) as well. It has been shown that wide variety of brain regions including the frontal lobe, anterior cingulate cortex, insula, amygdala, hypothalamus, periaqueductal gray
منابع مشابه
Contribution of the Nucleus Cuneiformis to the Antinociceptive Effects of Systemic Morphine on Inflammatory Pain in Rats
Introduction: The role of midbrain reticular formation, which includes the nucleus cuneiformis (NCF), as a crucial antinociceptive region in descending pain modulation has long been investigated. In this study, we tried to highlight the role of NCF in morphine-induced antinociception in formalin-induced pain model in rats. Methods: A total of 201 male Wistar rats weighing 260-310 g were used in...
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